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CS Alumnus and Dr. Papamichail’s Research Published in New Computational Biology Textbook

Pictured: Numaan Cheema (Class of 2021) and his son, Husain, who was born during the Spring 2021 semester.

Congratulations to CS alumnus Numaan Cheema (Class of 2021) and Dr. Dimitris Papamichail, who have authored a chapter, titled “Computational Tools for Synthetic Gene Optimization”, that has been included in New Frontiers and Applications of Synthetic Biology, a textbook published by Elsevier.

Dr. Papamichail shared background information on their research, included in the textbook as Chapter 12: “This study aims to examine the current state of the art developments in gene design software. Together with a thorough examination of well-established objectives in synthetic gene design, we describe our experiences using fifteen different gene design tools that enable synthetic biologists to re-design protein coding genes toward altered expression and other objectives. We also provide our insights on the direction of the field of synthetic gene design.”

Numaan, who completed mentored research with Dr. Papamichail in Spring 2021, shared his thoughts on working with Dr. Papamichail and their publishing accomplishment:  “As an undergraduate student with fairly limited exposure to Computational Biology, it was a daunting task going into its research.  Seeing my hesitance, Dr. Papamichail encouraged me like a Greek Mr. Miyagi with something along the lines of ‘We know the computation part of it, we’ll figure out the Biology of it as we go’. Truly honored and humbled to see the many months of hard work we did take form.”

Congratulations again to Numaan and Dr. Papamichail!

Official citation:
N. Cheema, G. Papamichail and D. Papamichail, Computational Tools for Synthetic Gene Optimization, New Frontiers and Applications of Synthetic Biology, edited by Vijai Singh, Elsevier, 2022.